Review



p16 ink-attac mice  (Unity Biotechnology)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Unity Biotechnology p16 ink-attac mice
    P16 Ink Attac Mice, supplied by Unity Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p16 ink-attac mice/product/Unity Biotechnology
    Average 90 stars, based on 1 article reviews
    p16 ink-attac mice - by Bioz Stars, 2026-03
    90/100 stars

    Images



    Similar Products

    ink attac mice  (MedChemExpress)
    95
    MedChemExpress ink attac mice
    Ink Attac Mice, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ink attac mice/product/MedChemExpress
    Average 95 stars, based on 1 article reviews
    ink attac mice - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier
    p16 ink-attac mice  (Unity Biotechnology)
    90
    Unity Biotechnology p16 ink-attac mice
    P16 Ink Attac Mice, supplied by Unity Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p16 ink-attac mice/product/Unity Biotechnology
    Average 90 stars, based on 1 article reviews
    p16 ink-attac mice - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ink-attac mice  (Unity Biotechnology)
    90
    Unity Biotechnology ink-attac mice
    Ink Attac Mice, supplied by Unity Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ink-attac mice/product/Unity Biotechnology
    Average 90 stars, based on 1 article reviews
    ink-attac mice - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ink-attac transgene mice  (Unity Biotechnology)
    90
    Unity Biotechnology ink-attac transgene mice
    Selective elimination of p16-positive senescent cells suppresses retinal dysfunction and degeneration in rod-specific cholesterol efflux-deficient mice. ( A ) Experimental design using Abca1/g1 -rod/-rod <t>;INK-ATTAC.</t> ( B ) Electroretinography waveform of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Each waveform and graph indicate the mean ± SEM. ( C ) The quantification of ERG (scotopic a-wave and b-wave) amplitudes. ( D ) Images of H&E staining. Scale bar : 50 µm. * P < 0.05; ** P < 0.01, two-way ANOVA followed by Bonferroni correction. Data are represented as mean ± SEM.
    Ink Attac Transgene Mice, supplied by Unity Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ink-attac transgene mice/product/Unity Biotechnology
    Average 90 stars, based on 1 article reviews
    ink-attac transgene mice - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ink-attac mice  (Wolters Kluwer Health)
    90
    Wolters Kluwer Health ink-attac mice
    Selective elimination of p16-positive senescent cells suppresses retinal dysfunction and degeneration in rod-specific cholesterol efflux-deficient mice. ( A ) Experimental design using Abca1/g1 -rod/-rod <t>;INK-ATTAC.</t> ( B ) Electroretinography waveform of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Each waveform and graph indicate the mean ± SEM. ( C ) The quantification of ERG (scotopic a-wave and b-wave) amplitudes. ( D ) Images of H&E staining. Scale bar : 50 µm. * P < 0.05; ** P < 0.01, two-way ANOVA followed by Bonferroni correction. Data are represented as mean ± SEM.
    Ink Attac Mice, supplied by Wolters Kluwer Health, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ink-attac mice/product/Wolters Kluwer Health
    Average 90 stars, based on 1 article reviews
    ink-attac mice - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    ink-attac transgenic mice  (GemPharmatech Co Ltd)
    90
    GemPharmatech Co Ltd ink-attac transgenic mice
    Selective elimination of p16-positive senescent cells suppresses retinal dysfunction and degeneration in rod-specific cholesterol efflux-deficient mice. ( A ) Experimental design using Abca1/g1 -rod/-rod <t>;INK-ATTAC.</t> ( B ) Electroretinography waveform of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Each waveform and graph indicate the mean ± SEM. ( C ) The quantification of ERG (scotopic a-wave and b-wave) amplitudes. ( D ) Images of H&E staining. Scale bar : 50 µm. * P < 0.05; ** P < 0.01, two-way ANOVA followed by Bonferroni correction. Data are represented as mean ± SEM.
    Ink Attac Transgenic Mice, supplied by GemPharmatech Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ink-attac transgenic mice/product/GemPharmatech Co Ltd
    Average 90 stars, based on 1 article reviews
    ink-attac transgenic mice - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Selective elimination of p16-positive senescent cells suppresses retinal dysfunction and degeneration in rod-specific cholesterol efflux-deficient mice. ( A ) Experimental design using Abca1/g1 -rod/-rod ;INK-ATTAC. ( B ) Electroretinography waveform of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Each waveform and graph indicate the mean ± SEM. ( C ) The quantification of ERG (scotopic a-wave and b-wave) amplitudes. ( D ) Images of H&E staining. Scale bar : 50 µm. * P < 0.05; ** P < 0.01, two-way ANOVA followed by Bonferroni correction. Data are represented as mean ± SEM.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration

    doi: 10.1167/iovs.65.10.29

    Figure Lengend Snippet: Selective elimination of p16-positive senescent cells suppresses retinal dysfunction and degeneration in rod-specific cholesterol efflux-deficient mice. ( A ) Experimental design using Abca1/g1 -rod/-rod ;INK-ATTAC. ( B ) Electroretinography waveform of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Each waveform and graph indicate the mean ± SEM. ( C ) The quantification of ERG (scotopic a-wave and b-wave) amplitudes. ( D ) Images of H&E staining. Scale bar : 50 µm. * P < 0.05; ** P < 0.01, two-way ANOVA followed by Bonferroni correction. Data are represented as mean ± SEM.

    Article Snippet: To generate mice deficient in Abca1 and Abcg1 in photoreceptors ( Abca1/g1 -rod/-rod ), Abca1 flox/flox /Abcg1 flox/flox ( Abca1/g1 f/f ) mice purchased from the Jackson Laboratory (021067) were crossed with mice with Rhodopsin-iCre75 transgene mice, which were originally provided by Dr. Ching-Kang Jason Chen., INK-ATTAC transgene mice were provided by Unity Biotechnology 33 and crossed with Abca1/g1 -rod/-rod to generate Abca1/g1 -rod/-rod ;INK-ATTAC.

    Techniques: Staining

    Selective elimination of p16-positive senescent cells suppresses AMD-associated phenotype and senescence without altering systemic lipid metabolism. Representative electron microscopy images showing RPE cells and Bruch's membrane ( A ), and the quantification of the number of intracellular lipids in RPE cells ( B ) and Bruch's membrane thickness ( C ). Scale bar : 2 µm. Note intracellular lipids in RPE cells ( arrow ) and thickened Bruch's membrane ( arrowhead ) in Abca1/g1 -rod/-rod . ( D ) mRNA expression of senescence markers ( p16 and p21 ) and Tnf-α in the retina and RPE/choroid complex isolated from Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Fat percentage ( E ), cholesterol ester in plasma and liver (F), and triglyceride and free fatty acids in adipose tissue ( G ) of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001, t -test. Data are represented as mean ± SEM.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration

    doi: 10.1167/iovs.65.10.29

    Figure Lengend Snippet: Selective elimination of p16-positive senescent cells suppresses AMD-associated phenotype and senescence without altering systemic lipid metabolism. Representative electron microscopy images showing RPE cells and Bruch's membrane ( A ), and the quantification of the number of intracellular lipids in RPE cells ( B ) and Bruch's membrane thickness ( C ). Scale bar : 2 µm. Note intracellular lipids in RPE cells ( arrow ) and thickened Bruch's membrane ( arrowhead ) in Abca1/g1 -rod/-rod . ( D ) mRNA expression of senescence markers ( p16 and p21 ) and Tnf-α in the retina and RPE/choroid complex isolated from Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. Fat percentage ( E ), cholesterol ester in plasma and liver (F), and triglyceride and free fatty acids in adipose tissue ( G ) of Abca1/g1 -rod/-rod and Abca1/g1 -rod/-rod ;INK-ATTAC. * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001, t -test. Data are represented as mean ± SEM.

    Article Snippet: To generate mice deficient in Abca1 and Abcg1 in photoreceptors ( Abca1/g1 -rod/-rod ), Abca1 flox/flox /Abcg1 flox/flox ( Abca1/g1 f/f ) mice purchased from the Jackson Laboratory (021067) were crossed with mice with Rhodopsin-iCre75 transgene mice, which were originally provided by Dr. Ching-Kang Jason Chen., INK-ATTAC transgene mice were provided by Unity Biotechnology 33 and crossed with Abca1/g1 -rod/-rod to generate Abca1/g1 -rod/-rod ;INK-ATTAC.

    Techniques: Electron Microscopy, Membrane, Expressing, Isolation